Regenerating Kidney Function with Mesenchymal Stem Cells

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Kidney disease is a growing health concern affecting millions worldwide. Fortunately, new regenerative medicine options like mesenchymal stem cells are proving to be effective for treating many types of kidney disease.

What Causes Kidney Disease?

There are many different kidney diseases, often caused by chronic degeneration, autoimmunity, or genetic factors. Diseases like diabetes and hypertension can damage the kidneys over time. Autoimmune conditions like lupus can also attack the kidneys. Some kidney diseases are caused by genetic issues that lead to kidney malfunction.

While the causes may vary, the end result is compromised kidney function. This is measured by GFR (glomerular filtration rate) scores. Normal GFR scores are around 60-100. Scores under 60 indicate kidney impairment. The lower the number, the worse the function. Stage 5 kidney failure (GFR under 15) requires dialysis or a transplant.

How Stem Cells Can Help

Mesenchymal stem cells have emerged as a regenerative medicine option for treating kidney disease. Mesenchymal stem cells are taken from sources like umbilical cord tissue. They can be grown and expanded in a lab and then injected back into patients.

Mesenchymal stem cells have some unique properties that make them well-suited for treating kidneys:

  • Immunomodulation: They can calm inflammation and autoimmunity attacking kidneys
  • Regenerative factors: They secrete growth factors and cytokines that stimulate repair
  • Kidney homing: When injected via IV, the cells home in on kidneys through a process called stem cell homing. Stem cell homing involves the release of chemical signals like cytokines and chemokines from injured kidney tissue. These signals interact with receptors on mesenchymal stem cells and activate them to migrate and home in on the kidneys. Additional factors like the presence of adhesion molecules also facilitate the stem cells’ ability to adhere to the injured kidney tissue.

Mesenchymal stem cells don’t directly replace damaged kidney cells. Rather, they help stimulate the body’s own repair mechanisms. This allows the kidneys to essentially heal and regenerate.

Success Treating Kidney Disease

Mesenchymal stem cells have been used to successfully treat patients with kidney disease ranging from stage 1 to stage 4. However, earlier intervention provides better outcomes.

In a recent study, one patient had stage 3 kidney failure with a GFR in the 40s. He received a mesenchymal stem cell IV treatment. Within just a few months his GFR score improved to over 60. For this patient, regenerating his kidney function allowed him to avoid dialysis and continue working.

IV Infusion Delivery Is the Most Effective Delivery

Delivering mesenchymal stem cells intravenously provides the best results for kidney regeneration. When injected, the cells travel through the body and naturally home in on injured tissues.

Other Health Benefits

Mesenchymal stem cell IVs provide benefits beyond kidney regeneration. The cells also accumulate in the lungs, heart, and other organs. This means they can simultaneously treat any co-existing conditions.

For example, the cells reduce inflammation in the lungs. They can also strengthen heart function by secreting regenerative and growth factors. This is why patients with both kidney and heart issues often improve in both areas after stem cell therapy.

Why Wait? Regenerate Your Kidneys Today!

Don’t wait until you need dialysis to take action. Stem cell therapy can help you regenerate kidney function now. Contact the Stem Cell Medical Center today to learn more about regenerating your kidney health with mesenchymal stem cells. The future of your kidney health is waiting.