Understanding the Difference Between Autologous and Allogeneic Stem Cell Transplantation

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Are you curious about the difference between Autologous and Allogeneic stem cell products? Stem cell transplantation is a common treatment for various diseases and disorders, including cancer. Autologous stem cell transplantation involves using a patient’s own stem cells, while Allogeneic transplantation involves using stem cells from a donor.

Autologous stem cell transplantation, as the name suggests, utilizes a patient’s own stem cells. These cells are harvested and stored prior to chemotherapy or radiation treatment, which can damage the bone marrow where stem cells are produced. Once the treatment is complete, the stored stem cells are infused back into the patient’s bloodstream, where they can travel to the bone marrow and produce new blood cells.

On the other hand, Allogeneic stem cell treatment uses stem cells from a donor. This can be either a matched related donor, such as a sibling, or an unrelated donor who has a matching tissue type. Allogeneic transplantation can be riskier than Autologous transplantation because the donor’s immune system may recognize the recipient’s body as foreign and attack it. However, this type of transplantation can be more effective in treating certain diseases, particularly those that involve a malfunctioning immune system.

If you are interested in learning more about cells transplantation and its potential benefits, our doctors at Stem Cell Medical Center are available to answer any questions you may have.

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American Cancer Society: Types of Stem Cell and Bone Marrow Transplants