Pancreatitis refers to swelling within the pancreas, a key abdominal organ needed for digestion and controlling blood sugar levels. Repeated bouts of pancreas inflammation can eventually become long-lasting or chronic, often requiring hospitalization and carrying major risk of serious health issues or even death. At this time, treatment options are limited for this painful condition beyond attempts to ease symptoms. However, an emerging treatment method intends to use stem cells to calm pancreatitis flare ups and promote healing of damaged pancreatic tissue.
Experiments show injected human umbilical cord MSCs accumulate in pancreatic lesions in severe acute pancreatitis models. MSC recipients display greatly reduced mortality, swelling, fluid buildup, duct blockage, enzyme leakage, and cell death/organ failure-associated inflammation. Stem cells provide greater protective effects when given soon after disease onset, and with higher cell numbers. Researchers suggest immune system modulation is the main mechanism since MSCs gather to hurt pancreatic tissue rapidly yet unlikely integrate and replace dead cells.
In another model, ANG-1 protein transfer into MSCs aims to spur new tiny blood vessel formation during recovery. As before, MSC treatment reduces tissue destruction markers, inflammatory cytokines, and enzyme levels compared to controls. However, ANG-1 transfected MSCs additionally benefit by improving vessel production. This highlights the importance of MSC healing molecules over direct cell replacement for reducing swelling and scarring.
Studies of interactions with pancreas cell components show MSCs release soluble signals suppressing activation/multiplication of scarring-promoting cells in chronic pancreatitis. Exposure to MSCs protects cells maintaining normal pancreatic structure.
Experiments also show human umbilical cord MSCs bring about programmed cell death among activated T lymphocytes. Similar localized immune suppression could ease pancreatic swelling. Surviving T cells may tune down destructive immune responses after contacting MSCs. Additionally, regulatory T cells may receive further activation to suppress nearby reactions.
Overall MSCs show encouraging potential for improving hard-to-treat pancreatitis unachievable with traditional drugs alone. Stem cell therapy may soon offer healing where standard interventions have failed patients with this inflammatory disease.
The Stem Cell Medical Center in Antigua leads in providing stem cell-based regenerative therapies for many conditions. Their state-of-the-art facilities and strict procedures deliver high-quality treatments using expert protocols developed by their U.S. board-certified medical team.
They offer a specialized protocol using anti-inflammatory mesenchymal stem cells obtained ethically from donated umbilical cord tissue to reduce pancreatitis inflammation and promote pancreatic tissue repair. The cells get administered intravenously to patients, utilizing their natural ability to migrate to injury sites and secrete healing/calming signals.
Over 200 million stem cells provide robust effects. Patients receive customized care by caring staff, with follow up after discharge to ensure optimal progress.
As a leading global provider of exceptional regenerative treatments, the Center stands ready to deliver lasting hope and recovery to pancreatitis patients. Their advanced protocols aim to succeed where standard options fail.
Contact us and schedule a consultation to see if you may benefit from regenerative treatments. Stem cell therapy could alleviate your pain and help you regain mobility.