Stem Cell Therapy for Traumatic Brain Injury – Rebuilding the Brain

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Rebuilding the Brain with Cord Stem Cells

Traumatic brain injury from blows or jolts to the head can have devastating lifelong impacts like physical disability, cognitive impairment, and emotional disorders. Excitingly, the Stem Cell Medical Center in Antigua is pioneering an umbilical cord stem cell treatment approach aiming to reverse disabling traumatic brain injury consequences.

What is Traumatic Brain Injury?

A traumatic brain injury occurs when an external mechanical force damages brain tissue. It is a silent epidemic, affecting over 10 million people a year worldwide. Besides initial injury-related disabilities, survivors often battle lifelong impairments to independence and quality of life.

Currently, therapeutic options only temporarily alleviate traumatic brain injury symptoms rather than correcting root causes. However, transformative solutions may arise from umbilical cord stem cell therapy research underway at the Stem Cell Medical Center.

Stem Cells: The Body’s Repair Tools

Stem cells are master cells that multiply and morph into other cell types. Naturally occurring in the body, they drive growth and healing. The brain harbors stem cell reservoirs actively churning out new neurons and support cells. After injury, these production zones accelerate, yielding more cells to replace damaged areas in limited self-repair attempts.

But often, the brain cannot rebuild enough, resulting in lingering deficits. The Stem Cell Medical Center leverages stem cells’ innate repair powers using two regenerative approaches:

  • Boosting patients’ own stem cells
  • Transplanting donor stem cells

Revving Up In-Resident Stem Cells

Animal research reveals that delivering growth-promoting proteins rouses dormant stem cells post-brain trauma. This mobilization enhances native cells’ proliferation and integration into injury sites.

Early findings indicate some spontaneous recovery of certain functions when internal stem cell activity is amplified. However, frequently, outside cell additions are still necessary to adequately mend damage causing disability.

Umbilical Cell Transplants Reconstruct Circuitry

Given restricted self-healing, the Stem Cell Medical Center transplants umbilical cord tissue stem cells into patient injury locations. These cells then develop into mature neurons, replacing dead ones and rebuilding neuro-infrastructure.

In animal testing, grafted umbilical mesenchymal stem cells morph into integrated replacement neurons. They also suppress inflammation and cell death while spurring native stem cell growth. These combined actions enable structural and functional repair that exceeds other stem cell options thus far.

Specifically, compared to other mesenchymal stem cells, umbilical versions excel since they are more youthful, actively multiply, and discharge larger amounts of healing chemicals. For example, umbilical transplants in brain-injured rats dramatically reduce inflammation, cell death, and neurological damage while kickstarting endogenous stem cell activity.

Regenerative Therapy on the Horizon

The Stem Cell Medical Center’s research constructs the basis for eventually shifting umbilical mesenchymal stem cell therapy into clinical practice for traumatic brain injury. Their efforts center on elucidating cellular mechanisms, optimizing transplant protocols, and validating safety.

Ongoing preclinical inquiries assess assorted cell doses, post-injury timing, and administration routes for maximal benefit with minimal adverse effects. Scientists closely track implanted cells to clarify localization over time. Rigorous animal model testing paves the path toward human studies and widespread patient access.

While more questions remain before widespread deployment, the Stem Cell Medical Center leads the momentum carrying cord stem cell therapy closer to realization each day. Their pioneering biological approaches summon stem cells’ formidable innate reparative powers to overturn injury-imposed disability.

Soon, the Stem Cell Medical Center may offer more than symptom relief for traumatic brain injury’s devastating impacts, instead may restore lifelong capability, independence, and quality of life by regenerating the brain from the cellular level up.